Description
COMPOSITION:
Sodium Hyaluronate I.P. 0.18%
CATEGORY:
Lubricant
PHARMACOLOGY:
Sodium hyaluronate is a derivative of hyaluronic acid and shares many of its beneficial properties. Sodium hyaluronate is a humectant, lubricant, and hypo-osmotic. It is found naturally in the eye where it is produced as a response to ocular surface damage. This hydrophilic polymer plays an important role in corneal wound healing as it promotes corneal epithelial repair and helps control localized inflammation. Sodium hyaluronate is also a lubricant with flow and deformation characteristics similar to those of the tear aqueous layer. Additionally, it reduces mucous strands in tears and is better at lowering tear osmolarity than glycerin.
MECHANISM OF ACTION:
Sodium hyaluronate functions as a tissue lubricant and is thought to play an important role in modulating the interactions between adjacent tissues. It forms a viscoelastic solution in water. Mechanical protection for tissues (iris, retina) and cell layers (corneal, endothelium, and epithelium) are provided by the high viscosity of the solution. Elasticity of the solution assists in absorbing mechanical stress and providing a protective buffer for tissues. In facilitating wound healing, it is thought that it acts as a protective transport vehicle, taking peptide growth factors and other structural proteins to a site of action. It is then enzymatically degraded and active proteins are released to promote tissue repair.
HYFRED enhances tear stability thus reducing loss by evaporation this in turn, helps to retain moisture in the eye and relieve the ocular inflammation associated with dry eyes. HYFRED substitutes help to reduce discomfort and reduce the risk of damage to the corneal epithelium.
INDICATIONS:
Dry Eye Syndrome, keratoconjunctivitis sicca, Eye irritation, Post Eye Surgery- Cataract Removal or Lasik.
CONTRAINDICATIONS:
In patients having a history of hypersensitivity towards any of the component of the ophthalmic solution.
DOSAGE:
One-Two Drops of HYFRED Eye Drops 2-3 times a Day or as directed by the eye doctor.
PRECAUTIONS:
- Do not swallow solution.
- If solution changes color or becomes cloudy, do not use.
- To avoid contamination, do not touch bottle tip on any surface and avoid direct contact with the eye.
- Close the bottle tightly immediately after use.
- Discontinue usage if experience any of the above adverse effects.
ADVERSE EFFECTS:
No adverse effects has been reported for sodium hyaluronate 0.18%.
INFORMATION TO PATIENT:
Follow the instructions that are provided by your doctor and if the adverse effect persists, discontinue the usage and contact your doctor immediately.
PRESENTATION:
HYFRED Eye Drops comes in a 10ml double ringed vial.
